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Blinn College • Bryan • Natural Science • Chemistry - CHEM

Organic Chemistry II CHEM-2425

  • Summer I 2013

  • Section SECTION_302 CRN-30420

  • 4 Credits

  • 06/03/2013 to 07/01/2013

  • Modified 06/03/2013

Meeting Times

7:30 to 9:25 am

9:35 to 11:30 am

LEC: S209

LAB: S226


Contact Information

Office: Room S237

Office Hours: M-R 4:00 - 5:00 pm



Phone: 209-7590

   and by appointment


This is an eCampus supplemented course


A continuation of CHEM 2423. The laboratory will include a multistep synthesis as well as the use of chromatography and qualitative analysis.


Prerequisites: CHEM 2423 with a grade of "C" or better.

Core Curriculum Statement

This course is not a core curriculum course.


1. Describe the use of three instrumental techniques that chemists use to identify compounds: mass spectrometry, infrared spectroscopy, NMR (1H and 13C), and UV/VIS spectroscopy.

2. Analyze the structural features that cause a compound to be aromatic, and explain how they react using benzene as an example.

3. Discuss and contrast the reactions of substituted benzenes and the methods used to synthesize compounds containing aromatic rings.

4. Compare the orientation of substitution in Electrophilic Aromatic Substitution of substituted aromatic compounds.

5. Discuss and contrast the reactions of aldehydes and ketones that undergo nucleophilic acyl substitution.

6. Relate the reactions of carbohydrates (Biomolecules) to the interrelated reactions of carbonyl compounds and alcohols.

7. Discuss and contrast the characteristics and reactions of carboxylic acids and nitriles.

8. Compare the reactions of carboxylic acid derivatives and those which undergo nucleophilic acyl substitution.

9. Discuss the acidity of the alpha-hydrogen and the reactions that occur at the alpha-carbon in substitution reactions.

10. Contrast carbonyl condensation reactions and their use for synthesizing compounds.

11. Compare the reactions of amines and heterocyclic compounds and devise an approach to synthesize these organic molecules.

12. Discuss the chemistry of amino acids, peptides and proteins.



Textbook: Organic Chemistry, McMurry, 8th Edition, Cengage, 2012.

Lab Manual: Chem2423/2425 OChem Lab Manual, Copy Stop Print and Postal

Organic Molecular Model Kit (Recommended)

Safety Equipment: safety eyewear (OSHA approved, with side shields - REQUIRED), aprons (Optional)

Course Requirements

Exams are a requirement.  There will be 4 exams worth 100 points each given about as indicated in the attached schedule.  Each of the exams will include all of the material covered through that stage of the course, i.e., all exams are comprehensive.  The lowest of the four grades will be dropped.  Format of the exams will vary.  If you miss an exam, this will be the grade that is dropped.  Make-up exams will be allowed in exceptional situations at my discretion, but only if taken before the graded exam is returned to the class.  The final exam is comprehensive and worth 150 pts.

Laboratory Experiments are a requirement.  The laboratory portion of this course counts for 25% of the course grade.  We have 10 experiments scheduled.  You will be graded on your lab report.  Lab reports will be due at the beginning of the lab 2 days after its completion.  The lowest of the lab grades will be dropped.  You will lose 5 points per class period for labs turned in late.

Quizzes are a requirement.  There will be a number of quizzes given during the semester.  There is no make-up offered for the quiz.  The top 10 quiz grades will be counted toward your final score.

The Final Exam is a requirement and is worth 20% of your final grade.

Eye protection is a requirement.  Students are responsible for purchasing appropriate eye protection and wearing eye protection during laboratories.  Appropriate eye protection for this class is safety goggles.


Grading and Grading Policy. CHEM 2425 (4 hr credit) is divided into both lecture (3 hr) and laboratory (1 hr) components. The lecture and Final will count toward 75% of the final grade and the lab will make up 25% of the final course grade. Your grades will be posted on eCampus so you will always know your standing in the course.

Exams (4 x 100 pts; best 3)

300 pts


Quizzes (top 10)

Laboratory Experiments  (10 x 25 pts)

  50 pts

250 pts


Final Exam

150 pts



750 pts


I do not curve, 900 pts (90.0%) is a guaranteed A; 800 pts (80.0%) is a B; etc.

Blinn College Policies

Blinn College policies on civility, class attendance; scholastic integrity; students with disabilities; final grade appeals; and electronic devices as stated in the Blinn College Student Handbook, Faculty Handbook, Blinn College Catalog and specific technical program handbooks. All policies, guidelines and procedures in the Student and Faculty Handbook and the Board and Administrative Policy Manuals are applicable to this course

Civility Statement

Members of the Blinn College community, which includes faculty, staff and students, are expected to act honestly and responsibly in all aspects of campus life. Blinn College holds all members accountable for their actions and words. Therefore, all members should commit themselves to behave in a manner that recognizes personal respect and demonstrates concern for the personal dignity, rights, and freedoms of every member of the College community, including respect for College property and the physical and intellectual property of others.

      Civility Notification Statement. If a student is asked to leave the classroom because of uncivil behavior, the student may not return to that class until he or she arranges a conference with the instructor; it is the student’s responsibility to arrange for this conference. 

      This statement reflects step one in a possible four step process.  The Incivility Protocol is detailed in the Blinn College Student Handbook.

Attendance Policy

The College District believes that class attendance is essential for student success; therefore, students are required to promptly and regularly attend all their classes. A record of attendance will be maintained from the first day of classes and/or the first day the student’s name appears on the roster through final examinations. If a student has one week’s worth of unexcused absences during the semester, he or she will be sent an e-mail by the College District requiring the student to contact his or her instructor and schedule a conference immediately to discuss his/her attendance issues. Should the student accumulate two weeks’ worth of unexcused absences, he or she will be administratively withdrawn from class.

There are four forms of excused absences recognized by the institution:

  1. observance of religious holy days—The student should notify his or her instructor(s) not later than the 15th day of the semester concerning the specific date(s) that the student will be absent for any religious holy day(s);
  2. representing the College District at an official institutional function;
  3. high school dual credit students representing the independent school district at an official institutional function; and
  4. military service.

Other absences may be considered excused at the discretion of the faculty member with appropriate documentation.  A student enrolled in a developmental course is subject to College District-mandated attendance policies. Failure to attend developmental classes shall result in removal from the course as defined by the College District.

It is the student’s responsibility to officially drop a class he or she is no longer attending.  To officially drop a class the student must obtain the class withdrawal form from Enrollment Services, complete the class withdrawal form, secure the required signatures, and return the completed form to Enrollment Services. The last day to drop with a Q is according to the Academic Calendar.

Scholastic Integrity

Blinn College does not tolerate cheating, plagiarism, or any other act of dishonesty with regard to the course in which you are enrolled.  The following text defines the faculty member’s responsibility with regard to the scholastic integrity expectation for this and all courses at Blinn College.

It is the responsibility of faculty members to maintain scholastic integrity at the College District by refusing to tolerate any form of scholastic dishonesty.  Adequate control of test materials, strict supervision during testing, and other preventive measures should be utilized, as necessary, to prevent cheating or plagiarism.  If there is compelling evidence that a student is involved in cheating or plagiarism, the instructor should assume responsibility and address the infraction.  Likewise, any student accused of scholastic dishonesty is entitled to due process as outlined in Blinn College Board Policy FLB (Local).  The Scholastic Integrity Policy is located in the Blinn College Student Handbook. In a case of scholastic dishonesty, it is critical that written documentation be maintained at each level throughout the process.

Students with Disabilities

Blinn College is dedicated to providing the least restrictive learning environment for all students. Support services for students with documented disabilities are provided on an individual basis, upon request. Requests for services should be made directly to the Office of Special Populations serving the campus of your choice.  For the Bryan campus, the Office of Special Populations (Administration Building) can be reached at (979)209-7251.  The Brenham, Sealy and Schulenburg campuses are served by the Office of Special Populations on the Brenham campus (Administration Building Room 104) and can be reached at (979)830-4157.  Additional information can be found at

Final Grade Appeal

If a student wishes to appeal a final grade in a course, Blinn College Board Policy FLDB (Local), Course Grade Complaints, outlines the timeline for the appeal and the four steps in the appeal.  This policy is located in the Blinn College Student Handbook.

Electronic Devices

All the functions of all personal electronic devices designed for communication and/or entertainment (cell phones, pagers, beepers, iPods, and similar devices) must be turned off and kept out of sight in all College District classrooms and associated laboratories.  Any noncompliance with this policy shall be addressed in accordance with the College District civility policy (administrative policy).  This information is contained in Blinn College Board Policy FLB (Local).

Course Policies

Classroom and Laboratory Conduct

When you enter the classroom or laboratory, you are entering a learning environment. As such, disruptions due to inappropriate behavior will not be tolerated. Talking, reading the newspaper, texting, and other activities that disrupt or detract from the classroom or laboratory learning experience will not be allowed. Eating and drinking are not allowed in Blinn classrooms. As previously mentioned, any visible food or drink container (even if it is sealed) is a safety violation in lab and will cause your immediate removal from the laboratory with a grade of zero being assigned for that experiment.


You must have enclosed chemical resistant safety goggles, not safety glasses for the lab.  You must also dress defensively.  It is recommended that you pack and carry an emergency “go bag” ready for lab which contains your goggles, appropriate clothing (sweats or scrubs) if needed, and appropriate closed-toe footwear so that should you forget, you will have clothes, shoes, and goggles that may be used that day for lab.  Failure to have safety goggles, dress defensively, or wearing flip-flops or sandals will cause you to be removed from the lab for a safety violation.  Failure to use your goggles while in the lab will also cause you to be removed from the lab. You are expected to put on goggles (protecting your eyes) the moment you enter the lab and not to remove them until you leave the laboratory. I am well aware that they are cumbersome, hot, and tend to fog up. These are for your protection and you do not have the option to decline to use them. You will receive one warning to put your goggles on. This first warning will be made the moment chemicals are brought into the room for you to use. The second warning given that day will result in your immediate removal from the laboratory and the assignment of a grade of zero (0) for that entire laboratory experiment (prelab, report, and postlab). Sliding the glasses/goggles up to protect your forehead or hairline is the most common method of getting dismissed from the lab. This will be rigidly enforced. A grade of zero received for a safety violation WILL NOT BE DISMISSED.

IMPORTANT!! If you forget your goggles you will not be allowed to perform the experiment. Your options are to

  1. Borrow a pair from a friend who may be on campus at that time.
  2. Buy another pair from the bookstore.
  3. Miss the lab (unexcused absence) and lose the points associated with that experiment.

You must wear enclosed footwear to the laboratory if a 'wet lab' is being performed. Enclosed footwear may be canvas, leather, steel toed work boots, or even plastic bags securely taped around your feet. If you come to the laboratory and chemicals are being used (other than ink, pencil, paper, and dry erase chemicals for a dry lab), you will be dismissed from the laboratory and receive a grade of zero (0) for that experiment. There are NO MAKE-UP LABS, if you miss the experiment you automatically lose all points associated with that experiment. If we are doing a "dry lab" or continuing in lecture or review, you do not need to have your safety glasses, you will not need enclosed footwear for dry labs.

NO water bottles, soft drinks, or food is allowed in the laboratory.  This is a safety violation that will result in your removal from the lab.

You should dress defensively for the laboratory. You are required to be covered from your neck to below your knees when performing an experiment in the chemistry laboratory.  You are almost guaranteed that you will ruin at least one piece of clothing in the laboratory. If you wish, you may purchase an apron or an artist's smock (lab coat) to protect your clothes. You may also wish to bring and wear rubber, latex, or nitrile gloves in lab. Gloves may help in preventing skin irritation, on the down side, gloves also tend to increase the unknowing transport of chemicals to your clothing and increase the occurrence of holes in your clothes.

Course eCampus

A CHEM 2425 eCampus homepage has been created and can be found at the following Internet address This site contains the course syllabus, assignments and any additional lecture notes for the chapter being covered. Note: Simply studying the notes or old PowerPoint lectures provided on eCampus will not be sufficient to ensure a good grade in this course.


An Incomplete can only be awarded under very specific conditions. Specifically, Incomplete's are awarded only if 90% of the course work has been completed. This means that something has happened at the end of the semester (documented illness, family emergency, catastrophic accident, etc.) and you are missing the last exam or the Final. An Incomplete cannot be given for a crisis at the middle of the semester or for being late for the Final Exam.

An Incomplete requires a contract be written, approved, and signed by the student, the instructor, and the division head prior to the "I" being given. No paperwork, no Incomplete. If you fail to complete the missing work in the specified time, a grade of F will be awarded. Incomplete's do not allow a student to retake the entire course to improve their grade.






June 3



Introduction, Review CHEM 2423


Safety Video, Review CHEM 2423

June 4



Mass Spectroscopy


Mass Spectroscopy, IR

June 5






June 6





Spectral Lab

June 7



Exam I


Diels Alder, Benzene, Aromaticity

June 10



Electrophilic Aromatic Substitution


Nitration of Methyl Benzoate

June 11





Borohydride reduction of Camphor

June 12



Carbonyl Compounds Nucleophilic Addition


Synthesis Lab I

June 13



Exam II


Grignard Reaction

June 14



Carboxylic Acids and Derivatives


Completion of Grignard exp.

June 17



Carboxylic Acids and Derivatives


Derivatives of Carboxylic Acids

June 18



Alpha Substitution of Carbonyl Compounds


Aldol Condensation

June 19



Carbonyl Condensation Reactions


Synthesis Lab II

June 20



Exam III


Completion of Aldol Condensation

June 21



Alpha Carbonyl Condensation Reactions


Reactions of Aldehydes and Ketones

June 21


Last day to drop with a Q

June 24



Alpha Carbonyl Condensation Reactions


Preparation of Indigo and Azo Dyes

June 25



Alpha Carbonyl Condensation Reactions


Amines and Heterocycles

June 26





Synthesis Lab III

June 27



Exam IV


Medicinal Chemistry

June 28



Medicinal Chemistry, Review

July 1



Final Exam, 7:30 am