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Blinn College • Bryan • Natural Science • Biology - BIOL

Biology for Science Majors I BIOL-1406

  • Fall 2013
  • Section SECTION_320 CRN-11400
  • 4 Credits
  • 08/26/2013 to 12/13/2013
  • Modified 01/09/2017

Meeting Times

MW  Lecture 7:05 pm to 8:20 pm  Lab 8:30 pm to 9:45 pm

Contact Information

Instructor: Michael Johanson

Office Hours

  • Wednesday, 5:45 PM to 6:45 PM, S117
  • Phone: 979-209-8261


Fundamental principles of living organisms will be studied, including physical and chemical properties of life, organization, function, evolutionary adaptation, and classification. Concepts of cytology, reproduction, genetics, and scientific reasoning are included. Laboratory activities are designed to reinforce lecture topics.


Prerequisite: Students must be college ready in reading, by means of appropriate exemption score by TSI or alternative test; or by completing READ 0306, or READ 0307, or DIRW 0326, or ESOL 0325 with a “C”or better, or by completing READ 0208 or ESOL 0226 with a passing grade.

Recommended: MATH 1314 – Successful completion of College Algebra or concurrent enrollment in higher-level mathematics.

Core Curriculum Statement

This is a Core Course in the 42-Hour Core Curriculum of Blinn College. As such, students will develop proficiency in the appropriate Intellectual Competencies, Exemplary Educational Objectives, and Perspectives.


  1. Describe the characteristics of life.
  2. Explain the methods of inquiry used by scientists.
  3. Identify the basic requirements of life and the properties of the major molecules needed for life.
  4. Compare and contrast the structures, reproduction, and characteristics of viruses, prokaryotic cells, and eukaryotic cells.
  5. Describe the structure of cell membranes and the movement of molecules across a membrane.
  6. Identify the substrates, products, and important chemical pathways in metabolism.
  7. Identify the principles of inheritance and solve classical genetic problems.
  8. Identify the chemical structures, synthesis, and regulation of nucleic acids and proteins.
  9. Describe the unity and diversity of life and the evidence for evolution through natural selection.
  10. Apply scientific reasoning to investigate questions and utilize scientific tools such as microscopes and laboratory equipment to collect and analyze data.
  11. Use critical thinking and scientific problem-solving to make informed decisions in the laboratory.
  12. Communicate effectively the results of scientific investigations.



Textbook: Campbell Biology, 9th Edition, 2011. Reece, Urry, Cain, Wasserman, Minorsky, and Jackson. Pearson Education, Inc. 

Lab Manual: Biology 1406 Laboratory Manual, Fall 2013, Richardson et. al. Copy Stop Print & Postal 


Textbook: Campbell Biology, 9th Edition, 2011. Reece, Urry, Cain, Wasserman, Minorsky, and Jackson. Pearson Education, Inc. 

Lab Manual: REFLECTIONS IN BIOLOGY – A Laboratory Manual – Volume I, On-line Edition, Greg Phillips: 2012

Course Requirements

All sections of this course regardless of location or modality will require:

  1. A minimum of three major exams
  2. A minimum of two laboratory exams
  3. A comprehensive final exam


The following are required components of a student’s final grade.

  1. Major exams account for at least 30% of the final grade.
  2. Laboratory exams designed to address both knowledge and skills and will account for at least 20% of the final grade.
  3. Minor Exams/Quizzes/Homework: Given at the discretion of the instructor. These materials will account for approximately 10% of the final grade.
  4. Additional Reports or Projects: Given at the discretion of the instructor.
  5. Student participation is assessed through the various assignments and will count for at least 10% of the final grade.
  6. Final Exam: Comprehensive exam covering the entire course. The comprehensive final exam will account for at least 20% of the final grade.


Homework 15(14pts each) + 2(7pts each)+1(6pts) = 230pts


4 exams (75 pts each)                                         = 300pts


Class Participation                                                =  70pts


Lab Exams(100 pts)                                             = 200pts


Final Exam                                                           = 200pts   


Total                                                                     1000pts



Grade scale


900-1000 = A       800-899 = B    700-799 = C   600-699 = D   599 and below = F  

Blinn College Policies

Blinn College policies on civility, class attendance; scholastic integrity; students with disabilities; final grade appeals; and electronic devices as stated in the Blinn College Student Handbook, Faculty Handbook, Blinn College Catalog and specific technical program handbooks. All policies, guidelines and procedures in the Student and Faculty Handbook and the Board and Administrative Policy Manuals are applicable to this course

Civility Statement

Members of the Blinn College community, which includes faculty, staff and students, are expected to act honestly and responsibly in all aspects of campus life. Blinn College holds all members accountable for their actions and words. Therefore, all members should commit themselves to behave in a manner that recognizes personal respect and demonstrates concern for the personal dignity, rights, and freedoms of every member of the College community, including respect for College property and the physical and intellectual property of others.

      Civility Notification Statement. If a student is asked to leave the classroom because of uncivil behavior, the student may not return to that class until he or she arranges a conference with the instructor; it is the student’s responsibility to arrange for this conference. 

      This statement reflects step one in a possible four step process.  The Incivility Protocol is detailed in the Blinn College Student Handbook.

Attendance Policy

The College District believes that class attendance is essential for student success; therefore, students are required to promptly and regularly attend all their classes. A record of attendance will be maintained from the first day of classes and/or the first day the student’s name appears on the roster through final examinations. If a student has one week’s worth of unexcused absences during the semester, he or she will be sent an e-mail by the College District requiring the student to contact his or her instructor and schedule a conference immediately to discuss his/her attendance issues. Should the student accumulate two weeks’ worth of unexcused absences, he or she will be administratively withdrawn from class.

There are four forms of excused absences recognized by the institution:

  1. observance of religious holy days—The student should notify his or her instructor(s) not later than the 15th day of the semester concerning the specific date(s) that the student will be absent for any religious holy day(s);
  2. representing the College District at an official institutional function;
  3. high school dual credit students representing the independent school district at an official institutional function; and
  4. military service.

Other absences may be considered excused at the discretion of the faculty member with appropriate documentation.  A student enrolled in a developmental course is subject to College District-mandated attendance policies. Failure to attend developmental classes shall result in removal from the course as defined by the College District.

It is the student’s responsibility to officially drop a class he or she is no longer attending.  To officially drop a class the student must obtain the class withdrawal form from Enrollment Services, complete the class withdrawal form, secure the required signatures, and return the completed form to Enrollment Services. The last day to drop with a Q is according to the Academic Calendar.

Scholastic Integrity

Blinn College does not tolerate cheating, plagiarism, or any other act of dishonesty with regard to the course in which you are enrolled.  The following text defines the faculty member’s responsibility with regard to the scholastic integrity expectation for this and all courses at Blinn College.

It is the responsibility of faculty members to maintain scholastic integrity at the College District by refusing to tolerate any form of scholastic dishonesty.  Adequate control of test materials, strict supervision during testing, and other preventive measures should be utilized, as necessary, to prevent cheating or plagiarism.  If there is compelling evidence that a student is involved in cheating or plagiarism, the instructor should assume responsibility and address the infraction.  Likewise, any student accused of scholastic dishonesty is entitled to due process as outlined in Blinn College Board Policy FLB (Local).  The Scholastic Integrity Policy is located in the Blinn College Student Handbook. In a case of scholastic dishonesty, it is critical that written documentation be maintained at each level throughout the process.

Students with Disabilities

Blinn College is dedicated to providing the least restrictive learning environment for all students. Support services for students with documented disabilities are provided on an individual basis, upon request. Requests for services should be made directly to the Office of Special Populations serving the campus of your choice.  For the Bryan campus, the Office of Special Populations (Administration Building) can be reached at (979)209-7251.  The Brenham, Sealy and Schulenburg campuses are served by the Office of Special Populations on the Brenham campus (Administration Building Room 104) and can be reached at (979)830-4157.  Additional information can be found at

Final Grade Appeal

If a student wishes to appeal a final grade in a course, Blinn College Board Policy FLDB (Local), Course Grade Complaints, outlines the timeline for the appeal and the four steps in the appeal.  This policy is located in the Blinn College Student Handbook.

Electronic Devices

All the functions of all personal electronic devices designed for communication and/or entertainment (cell phones, pagers, beepers, iPods, and similar devices) must be turned off and kept out of sight in all College District classrooms and associated laboratories.  Any noncompliance with this policy shall be addressed in accordance with the College District civility policy (administrative policy).  This information is contained in Blinn College Board Policy FLB (Local).

Course Policies

Extra Credit

There are some extra credit opportunities in some of the home work assignments and there may be some on the exams (not the final). However, the credit awarded will be minimal and the total points awarded will not exceed the maximum points possible for an assignment. The purpose of the extra credit questions are to enrich the students educational experience rather than to make up for previous academic deficiencies.







Lecture Topic

Laboratory Topic






First Day /Intro to Biol

Intro to Biol/Chemical Context of Life

Labs 1 & 2 – Safety/Process of Science

Lab 3 – The Scientific Method






Holiday-Labor Day

Water and Life                                  HW 1&2 due

Holiday-Labor Day

Lab 4 and 5 – Exp. Design/Graphing






Carbon and Molecular Diversity   HW 3 due

Large Biological Molecules            HW 4 due

Lab 6 – Metric Measurement

Lab 6 – Metric Measurement cont’d






Large Biological Molecules

Test #1 (1-5)                                        HW 5 due

Organic Molecules Activity

Lab 7 – Testing for Organic Molecules





A Tour of the Cell/          



Lab 8 – Microscopy





Membrane Transport/                  HW 6&19 due

Cell Communication

Lab 9 – Observing Cells in Action

Lab 10 – Prokaryotic and Eukaryotic Cells






Intro to Metabolism                    HW 7&11 due

Test #2  (6-8, 11, 19)                 HW 8 due

Lab 11 – Membrane Transport

Lab 11 – Membrane Transport cont’d






Cellular Respiration              

Cellular Respiration

Cellular Respiration Concept Maps

Review for Lab Practical #1






Photosynthesis                           HW 9 due


Lab Exam #1 (Monday, 10/21)

Lab 12 – Spectrophotometry






The Cell Cycle                             HW 10 due

Test #3  (9-10, 12)                     HW  12 due

Lab 17 – Mitosis

Lab 13 – Chromatography






Meiosis and Sexual Life Cycle

Molecular Basis of Inheritance HW 13 due

Lab 14 – Photosynthesis

Lab 14 – Photosynthesis cont’d

12 Q





From Gene to Protein                HW 16 due From Gene to Protein               

Gene Expression Concept Maps

Lab 15 – DNA Isolation






Regulation of Gene Expression HW 17 due

Test #4 (13, 16-18)                      HW 18 due

Lab 16 – Restriction Endonucleases

Lab 18 – Mendelian Genetics






Mendel and the Gene Idea

Thanksgiving Holiday

Lab 18 – Mendelian Genetics cont’d Thanksgiving Holiday






Mendel and the Gene Idea

Chromosomal Basis of Inheritance HW 14 due

Review for Lab Exam #2

Lab Exam #2 (Wednesday, 12/04)






Chromosomal Basis of Inheritance

HW 15 due

Review and Assessment



Final Exam

Section 320, Friday 12/13, from 5:30 pm to 7:30 pm in lecture room S-225


* In case of course schedule changes, updates will be posted on eCampus and notified in class.

* Homework assignments are due at 7pm on the due date.

  • § We covered only part of the chapter.

Q Q-drop, last day to withdraw with a “Q” is Friday, November 15, 2013.


Course calendar and related activities
When Topic Notes

BITC 2471

GMP Procedures and Documentation

General Class Schedule Overview






Course Title


Semester Credit Hrs

Min Cont Hrs

Max Cont Hrs




GMP Procedures and Documentation








Student Assignment

Total hours




Introduction to Therapeutics Manufacturing and GMP Procedures and Documentation

Therapeutics Manufacturing, Industry overview – Biologics Discovery, Development, Scale Up, Approval, and Commercialization



4 hours




Module 1 –

Lesson 1, Introduction, General History – The Food and Drug Administration and the evolution of current Good Manufacturing Practices – Drug and Biologics


Promoting Safe and Effective Drugs for 100 years - FDA



4 hours


Module 1

Lesson 2, Importance GMP Procedures, documentation, regulatory compliance

Reading: Handout “Thalidomide Story”




4 hours



Module 2 –Principles of Documentation

Lesson 1 – Why Document

Lesson 2 – Controlled Documents


Documentation Basics pp9 3-95

Sulfanilamide Tragedy



4 hours




Module 2

Lesson 3 –Data and Information Entries

Lesson 4 – Document Flow and Document Control


Documentation Basics, pp 29, 81-82, 84-86




4 hours



1st EXAM

Module 2

Lesson 5 – Change Control

Lesson 6 – Deviation/Discrepancy Reporting

Lesson 7 - Internal Auditing/Vendor Auditing

Lesson 8 – Training, Training Records

Test – Modules 1 and 2


Documentation Basics, pp 31-38

Documentation Basics, pp 83-84



4 hours





Module 3 – Identifiers –Tagging

Document Control Numbers, System Identification Numbers – Alpha Numeric Systems


Documentation Basics, pp 3-14



Draft Control Document Template

Prepare a Standard Operating Procedure (topic - student discretion approved by instructor)

4 hours




Module 3 – Identifiers –Tagging

Document Control Numbers, System Identification Numbers – Alpha Numeric Systems

Module 4 – Technical Writing

Lesson 1 – Clarity

Lesson 2 – Consistency




Prepare a draft Deviation/Discrepancy Standard Operating Procedure

4 hours




Module 4 - Technical Writing

Lesson 3 - Section Heading

Lesson 4 - Lists

Lesson 5 - Graphics


4 hours




Module 4 Technical Writings

Review BPRS drafts - discuss

Lesson 6 – Tables

Lesson 7 - Templates


Handout - Templates



6 hours




Module 5 – Required GMP Documentation, Biologics, Drugs and Device –

Review CGMP 21 CFR Part 210/211, 600 and 820

Lesson 1 – Quality Systems

Lesson 2 - Research and Development (R&D) Documents

Reading: Documentation Basics, pp 43-55, 87-95




4 hours



2nd Exam

Module 5 - Required GMP Documentation

Lesson 3 –Logbooks

Lesson 4 – Standard Operating Procedures

Lesson 5 – Batch Production Records

Lesson 6 – Validation and Qualification Documents

EXAM Modules 3,4 and 5

Module 6 – Putting it all together


Documentation Basics, pp 39-41, 69-76, 93

Documentation Basics, pp 27-38

Documentation Basics, pp 96-105

Documentation Basics, pp 107 -129


Written: Prepare Simple Batch Production Record



4 hours


Module 6 – Putting it all together

Quality System – New product development

Reading:   Forgotten Good “Laboratory Practices (GLP)” 1999 and “FDA Animal Rule”

4 hours



Project – New Therapeutic Product

Discovery, Development, Clinical Trials, Scale up, Documentation, Commercialization.




Product, Project Plan, Master Plan, Validation Master Plan, Facilities Validation Plan, Process and Cleaning Validation Plan, BPRs SOPs

2 hours



Project – New Company, New Product.

Discovery, Development, Clinical Trials, Scale up, Documentation, Commercialization.



Handout, Denileukin diftitox (Ontak)



Product, Project Plan, Master Plan, Validation Master Plan, Facilities Validation Plan, Process and Cleaning Validation Plan, BPRs SOPs

4 hours


Final Exam

Project – New Company, New Product.

Discovery, Development, Clinical Trials, Scale up, Documentation, Commercialization.

Project Final Reports Due 09 Dec 14

Final Exam




Product, Project Plan, Master Plan, Validation Master Plan, Facilities Validation Plan, Process and Cleaning Validation Plan, BPRs SOPs

4 hours




Total Contact Hours   64