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Anatomy & Physiology II > Curricula Vitae

Instructors


Michael Ko

Education

M.B.A., University of Houston Bauer School of Business, Houston, Texas. 2004.

 

Ph.D., Biomedical Sciences (Pharmacology), Kent State University/Northeastern Ohio Universities College of Medicine, Kent, Ohio.  1998.

 

B.A., Biology, University of Dallas, Irving, Texas. 1988.

Experience

full-time Lecturer

August 2015-current

Blinn College, Bryan, TX

- General Biology I (BIOL 1406)

- Anatomy & Physiology I and II (BIOL 2401 & 2402)

- Introduction to Physiology (BIOL 2404)

 

Research Assistant Professor

August 2004 - current

Texas A&M University, College Station, TX

 

part-time Lecturer

January 2005 - July 2015

Blinn College, Bryan, TX

 

 

Publications

29.  Chang, J., Shi, L., Ko,M.L., and Ko, G.  Circadian regulation of mitochondrial dynamics in retinal photoreceptors.  JBR, 33(2): 151-165, 2018.  PMID: 29671706.

 

28.  Shi, L., Chang, J., Yu, F., Ko, M.L., and Ko, G.  The contribution of L-type Cav1.3 channels to retinal light responses.  Front. Mol. Neurosci., 10: 394, 2017.  PMID: 29259539.

 

27.  Retinoschisin facilitates the function of L-type voltage-gated calcium channels.  Shi, L., Ko, M.L., and Ko, G.  Front. Cell. Neurosci. 11: 232, 2017.  PMID: 28848397.

 

26.  Kim, A.J., Chang, J., Shi, L., Chang, R., Ko, M.L., and Ko, G.  The effects of metformin on obesity-induced dysfunctional retinas.  IOVS, 58: 106-118, 2017.

 

25.  Shi, L., Kim, A.J., Chang, R., Ying, W., Ko, M.L., Zhou, B., and Ko, G.  Deletion of miR-150 exacerbates retinal microvascular overgrowth in high-fat-diet induced diabetic mice.  PLoS ONE, 11(6): e0157543, 2016.  PMID: 27304911; PMCID: 4909316.

 

24.  Huang, C., Shi, L., Lin, C., Kim, A.J., Ko, M.L., and Ko, G.  A new role of AMP-activated protein kinase (AMPK) in the circadian regulation of L-type voltage-gated calcium channels (L-VGCCs) in late-stage embryonic retinal photoreceptors.  J. Neurochem., 135: 727-741, 2015.  PMID: 26337027; PMCID: 4636938; NIHMS: 720740.

 

23.  Chang, R., Shi, L., Huang, C., Kim, A.J., Ko, M.L., Zhou, B., and Ko, G.  High-fat-diet induced retinal dysfunction.  IOVS, 56: 2367-2380, 2015.  PMID: 25788653; PMCID: 4407693.

 

22.  Shi, L., Ko, M.L., Park, S., Ko, S., Kim, A.J., and Ko, G.  Peptide Lv augments L-type voltage-gated calcium channels through vascular endothelial grpwth factor receptor 2 (VEGFR2) signaling.  Biochimica et Biophysica Acta (BBA) Mol. Cell Res., 1853: 1154-1164, 2015.  PMID: 25698653; PMCID: 4382007; NIHMS: 664987.

 

21.  Ko, M.L., Shi, L., Huang, C., Park, S., Hong, M., Wu, C., and Ko, G.  Chicken embryos as a potential new model for early onset type I diabestes.  J. Diabetes Res., 354094, 2014.  PMID: 25133191; PMCID: 4122024. 

 

20.  Ko, M.L., Shi, L., Huang, C., Grushin, K., Park, S., and Ko, G.  Circadian phase-dependent effect of nitric oxide on L-type voltage-gated calcium channels in avian cone photoreceptors.  J. Neurochem., 127: 314-328, 2013.  PMID: 23895452; PMCID: 4112736; NIHMS: 512095.

 

19.  Huang, C., Ko, M.L., and Ko, G.  A new functional role for mechanistic/mammalian target of rapamycin complex 1 (TORC1) in the circadian regulation of L-type voltage-gated calcium channels in avian cone receptors.  PLoS ONE, 8(8): e73315, 2013.  PMID: 23977383; PMCID: 3747127.

 

18.  Shi, L., Ko, M.L., Abbott, L., and Ko, G.  Identification of peptide Lv, a novel putative neuropeptide that regulates the expression of L-type voltage-gated calcium channels in photoreceptors.  PLoS ONE, 7(8): e43091, 2012.  PMCID: 3418253.

 

17.  Huang, C.-Y., Ko, M. L., Vernikovskaya, D. I., Ko, G. Y.-P.  Calcineurin serves in the circadian output pathway to regulate the daily rhythm of L-type voltage-gated calcium channels in the retina.  J. Cellular Biochemistry, 113: 911-922, 2012.  NIHMS: 342130.

 

16.  Ko, M. L., Shi, L., Tsai, J.-Y., Young, M.E., Neuendorff, N., Earnest, D.J. and Ko, G.Y.-P.  Cardiac-specific mutation of Clock alters the quantitative measurements of physical activities without changing behavioral circadian rhythms.  J. Biological Rhythms, 26:412-422, 2011.  PMCID: 3181102; NIHMS: 325298.

 

15.  Ko, M. L.*, Shi, L.*, Grushin, K., Nigussie, F., Ko, G. Y.-P.  Circadian profiles in the embryonic chick heart: L-type voltage-gated calcium channels and signaling pathways.  Chronobiology International, 27: 1673-1696, 2010. PMID: 20969517; PMCID: 3155203; NIHMS: 316276.

 

14.  Shi, L., Ko, M. L., and Ko, G. Y.-P.  Rhythmic expression of microRNA-26a regulates the L-type voltage-gated calcium channel α1C subunit in chicken cone photoreceptors.  J. Biological Chemistry, 284: 25791-25803, 2009.

 

13.  Jian, K., Barhoumi, R., Ko, M. L., and Ko, G. Y.-P.  The inhibitory effect of somatostatin-14 on L-type voltage-gated calcium channels in cultured cone photoreceptors requires intracellular calcium.  J. Neurophysiology, 102:1801-1810, 2009.

 

12.  Ko, M. L., Jian, K., Shi, L., and Ko, G. Y.-P.  Phosphatidylinositol 3 Kinase-Akt signaling serves as a circadian output in the retina.  J. Neurochemistry, 108: 1607-1620, 2009.

 

11.  Ko, M. L., Shi, L., and Ko, G. Y.-P.  Circadian controls outweigh acute illumination effects on the activity of extracellular signal-regulated kinase (ERK) in the retina.  Neuroscience Letters, 451:74-78, 2009.

 

10.  Shi, L., Jian, K., Ko, M. L., Trump, D., and Ko, G.Y.-P.  Retinoschisin, a new binding partner for L-type voltage-gated calcium channels in the retina.  J. Biological Chemistry, 284: 3966-3975, 2009.

 

9.  Ko, M. L., Liu, Y., Shi, L., Trump, D., and Ko, G.Y.-P.  Circadian regulation of retinoschisin in the chick retina.  Invest Ophthalmol Vis Sci, 49: 1615-1621, 2008.

 

8.  Ko, M. L., Liu, Y., Dryer, S.E., and Ko, G.Y.-P.  The expression of L-type voltage-gated calcium channels in retina photoreceptors is under circadian control.  J. Neurochemistry. 103: 784-792; 2007.

 

7.  Ko G.Y.-P., Ko M.L. and Dryer S.E.  Circadian and cAMP-dependent modulation of retinal cone cGMP-gated channels does not require protein synthesis or calcium influx through L-type channels.  Brain Research, 1021:277-280, 2004.

 

6.  Ko G.Y.-P., Ko M.L. and Dryer S.E.  Circadian regulation of cGMP-gated channels of verbebrate cone photoreceptors: Role of cAMP and Ras.  J. Neuroscience, 24:1296-1304, 2004.

 

5.  Ko G., Ko M.L. and Dryer S.E.  Circadian phase-dependent modulation of cyclic GMP gated channels of cone photoreceptors by dopamine and D2 agonists.  J. Neuroscience 23: 3145-3153, 2003.

 

4.  Ko G., Ko M.L. and Dryer S.E.  Circadian regulation of cGMP-gated cationic channels of chick retinal cones: Erk MAP kinase and Ca2+/calmodulin-dependent protein kinase II.  Neuron 29: 255-266, 2001.

 

3.  Ko G., Ko M.L. and Dryer S.E.  Developmental expression of retinal cone cGMPgated channels: evidence for rapid turnover and trophic regulation.  J. Neurosci. 21: 221-229, 2001.

 

2.  Henkel J., Du H., Yang P., Qyang Y., Kansra S., Ko M.L., Kim H. and Marcus S.  Bob1, a Gim5/MM-1/Pfd5 homolog, interacts with the MAP kinase kinase Byr1 to regulate sexual differentiation in the fission yeast, Schizosaccharomyces pombe.  Differentiation 67: 98-106, 2000.

 

1.  Ko M.L., King M.A., Gordon T. and Crisp T.  The effects of aging on spinal neurochemistry in the rat.  Brain Res. Bull. 42: 95-98, 1997.